GW-0742 Solution, 600MG (20mg/mL)

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GW-0742


GW-0742 is a mixed PPAR-B agonist antagonist, dose dependent. It also has weak activity at multiple nuclear receptors.

It is antagonistic to androgen receptors and VDR. In silico modeling suggests it has effects on thyroid hormone receptors.


GW0742 has been shown to ameliorate experimentally induced pancreatitis in mice. It also prevents hypertension in diet-induced obese mice. and is also being investigated as a potential antidiabetic agent. It is also an anti-inflammatory agent.


Concentration

20mg/ml.

half-life

24 hours.


DISCLAIMER

This material is sold for use in laboratory research only. Terms of sale apply. Not for human consumption, nor for medical, veterinary or domestic use. Please familiarize yourself with our DISCLAIMER before ordering.



Included is a precision pipette marked per 0.2 ml!
Shake well before use.

Data sheet

GW-0742 – Solution, 600mg (20mg/mL)

Application Potent PPARβ and PPARδ agonist
CAS 317318-84-6
Molar Mass 471.5 g/mol
Chemical Formula C21H17F4NO3S2
IUPAC Name 2-[4-[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl]methylsulfanyl]-2-methylphenoxy]acetic acid
Synonyms GW0742, 317318-84-6, GW 0742, GW-0742, GW0742X, GW610742, GW-0742X, CHEMBL38508, CHEBI:79991, {4-[({2-[3-Fluoro-4-(Trifluoromethyl)phenyl]-4-Methyl-1,3-Thiazol-5-Yl}methyl)sulfanyl]-2-Methylphenoxy}acetic Acid, SR-05000000447, 3tkm, GW 0742X, GWdelta 0742, GW 610742, GW-610742, DSSTox_CID_20760, DSSTox_RID_79591, DSSTox_GSID_40760, MLS006011159
Storage Store at room temperature, tightly sealed, away from heat, light and moisture.
Solubility Soluble in DMSO, PEG 400
Organoleptic Profile Clear liquid
Physical Form Solution in PEG 400
Specification 20mg/mL ±5%
Terms This material is sold for laboratory research use only. Terms of sale apply. Not for human consumption, nor medical, veterinary, or household uses. Please familiarize yourself with our Terms & Conditions prior to ordering.

 


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